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SHORT COMMUNICATION
Year : 2022  |  Volume : 27  |  Issue : 2  |  Page : 166-168

Association between socioeconomic status and homeostasis model assessment-insulin resistance index and mediating variables at the first trimester of pregnancy


1 Department of Mathematical Sciences, Isfahan University of Technology, Isfahan, Iran
2 Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
3 Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
4 Department of Health Education And Promotion, Social Determinants Of Health Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5 Department of Health, Azad University of Firoozabad Branch, Fars, Iran
6 Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd. Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Correspondence Address:
Dr. Masoomeh Goodarzi-Khoigani
Child Growth and Development Research Center, Research Institute for Primordial Prevention of Noncommunicable Disease, Isfahan University of Medical Sciences, Isfahan
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnmr.IJNMR_451_20

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Background: Some studies have shown that Socioeconomic Status (SES) is positively related to insulin resistance among different population groups, except for pregnant women. Therefore, we examined the relationship between SES and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) index as well as mediating variables. Materials and Methods: This study was performed on 138 primiparous healthy women at 6–10 weeks of pregnancy. The association between SES and HOMA-IR was analyzed by regression analysis, and mediating variables were determined by mediation analysis. Results: SES score was positively correlated with HOMA-IR index [β = 0.02, t101 = 2.20, p = 0.03, 95% CI: (0.00–0.05]. The higher percentage of mediation was related to maternal weigh (70.80%). Job activity had a protective effect on the association between SES and HOMA-IR (-62.50%). The total percentage of two mediators was 25%. Conclusions: The positive relationship between SES and (HOMA-IR) in early pregnancy may provide a way to control this condition.


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